ADHF results in millions of hospitalizations worldwide each year, including nearly 2 million in the US.2

Patients with ADHF experience difficulty breathing, fatigue, and edema (swelling) due to fluid back-up in the lungs and other parts of the body (congestion). The condition requires immediate treatment to remove excess fluid in a process called decongestion.


Complete decongestion is the goal of ADHF treatment, as residual congestion at hospital discharge is the strongest predictor of rehospitalization and death.4,5,6As many as half of ADHF patients are discharged from the hospital not fully decongested,about 25% of ADHF patients are readmitted to the hospital within one month and 50% are readmitted in 6 months.7,8,9